MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1321 · 46 genes shown · anchor whiB1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1321 (requalified) — endonuclease NucS Rv1321 Rv1322 (family_assigned) — hypothetical protein Rv1322 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv1318c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv1318c whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA alkA (family_assigned) — bifunctional regulatory protein/DNA repair enzyme alkA Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 secG (family_assigned) — preprotein translocase subunit SecG secG ogt (requalified) — methylated-DNA--protein-cysteine methyltransferase ogt Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c Rv1320c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv1320c Rv1319c (requalified) — adenylate cyclase Rv1319c Rv3909 (dark) — hypothetical protein Rv3909 sigA (requalified) — RNA polymerase sigma factor sigA sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c ndkA (requalified) — nucleoside-diphosphate kinase ndkA pykA (requalified) — pyruvate kinase pykA cpdA (requalified) — 3'%2C5'-cyclic adenosine monophosphate phosphodies cpdA relA (family_assigned) — RelA/SpoT family protein relA moaA2 (requalified) — GTP 3'%2C8-cyclase MoaA moaA2 moaA1 (requalified) — cyclic pyranopterin monophosphate synthase moaA1 clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB helZ (requalified) — DEAD/DEAH box helicase helZ xthA (requalified) — exodeoxyribonuclease III protein XthA xthA Rv3394c (family_assigned) — DNA polymerase Y family protein Rv3394c Rv3194c (family_assigned) — PDZ domain-containing protein Rv3194c Rv3196 (family_assigned) — hypothetical protein Rv3196 clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv1998c (family_assigned) — isocitrate lyase/phosphoenolpyruvate mutase family Rv1998c Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c secE1 (requalified) — preprotein translocase SecE secE1 secY (family_assigned) — preprotein translocase subunit SecY secY yidC (requalified) — membrane protein insertase YidC yidC secA1 (family_assigned) — protein translocase subunit SecA secA1 secA2 (requalified) — accessory Sec system translocase SecA2 secA2 ftsY (requalified) — signal recognition particle-docking protein FtsY ftsY tagA (requalified) — DNA-3-methyladenine glycosylase I tagA whiA (family_assigned) — DNA-binding protein WhiA whiA Rv2239c (family_assigned) — hypothetical protein Rv2239c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.