MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1295 · 46 genes shown · anchor thrB · open gene page → · ← back to 1 hop

Evidence: Min score 0
thrC (requalified) — threonine synthase thrC thrB (requalified) — homoserine kinase thrB thrA (requalified) — homoserine dehydrogenase thrA ilvA (requalified) — threonine ammonia-lyase ilvA serC (requalified) — phosphoserine transaminase serC argS (requalified) — arginine--tRNA ligase argS lysA (requalified) — diaminopimelate decarboxylase lysA ask (requalified) — aspartate kinase ask leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD ilvC (requalified) — ketol-acid reductoisomerase ilvC snzP (family_assigned) — pyridoxal 5'-phosphate synthase lyase subunit PdxS snzP sdaA (requalified) — L-serine ammonia-lyase sdaA serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM ilvE (requalified) — branched-chain amino acid aminotransferase ilvE metH (requalified) — methionine synthase metH asd (requalified) — aspartate-semialdehyde dehydrogenase asd metA (requalified) — homoserine O-acetyltransferase metA dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuB (requalified) — 3-isopropylmalate dehydrogenase leuB ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG serA2 (requalified) — D-3-phosphoglycerate dehydrogenase SerA serA2 serB2 (requalified) — phosphoserine phosphatase SerB serB2 Rv3684 (requalified) — lyase Rv3684 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA gltS (requalified) — glutamate--tRNA ligase gltS ileS (requalified) — isoleucine--tRNA ligase ileS metS (requalified) — methionine--tRNA ligase metS proS (requalified) — proline--tRNA ligase proS leuS (requalified) — leucine--tRNA ligase leuS dapF (requalified) — diaminopimelate epimerase dapF murE (requalified) — UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-d murE dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB asnB (requalified) — asparagine synthase (glutamine-hydrolyzing) asnB purA (requalified) — adenylosuccinate synthase purA argG (requalified) — argininosuccinate synthase argG nadB (requalified) — L-aspartate oxidase nadB leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuA (requalified) — 2-isopropylmalate synthase leuA Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvX (family_assigned) — acetolactate synthase large subunit ilvX

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.