Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1226c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1226c (family_assigned) — PH domain-containing protein Rv1226c Rv1227c (family_assigned) — PH domain-containing protein Rv1227c Rv1225c (family_assigned) — HAD-IIA family hydrolase Rv1225c Rv3365c (requalified) — sensor histidine kinase Rv3365c lpqX (dark) — hypothetical protein lpqX eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 Rv1234 (requalified) — general stress protein Rv1234 arfC (family_assigned) — hypothetical protein arfC adnB (requalified) — ATP-dependent DNA helicase AdnB adnB eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 moeA2 (requalified) — molybdopterin molybdenumtransferase moeA2 Rv3662c (requalified) — oxidoreductase Rv3662c Rv1157c (dark) — hypothetical protein Rv1157c Rv3278c (family_assigned) — PH domain-containing protein Rv3278c pssA (requalified) — CDP-diacylglycerol--serine O-phosphatidyltransfera pssA pstP (requalified) — phosphoserine/threonine phosphatase PstP pstP cmk (requalified) — (d)CMP kinase cmk Rv3760 (family_assigned) — membrane protein Rv3760 rsmD (requalified) — 16S rRNA (guanine(966)-N(2))-methyltransferase Rsm rsmD Rv3363c (family_assigned) — DUF742 domain-containing protein Rv3363c Rv3362c (family_assigned) — ATP/GTP-binding protein Rv3362c Rv3364c (requalified) — serine protease inhibitor Rv3364c mfpA (requalified) — pentapeptide repeat protein MfpA mfpA Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB lppR (family_assigned) — sensor domain-containing protein lppR lppL (family_assigned) — hypothetical protein lppL lpqK (family_assigned) — serine hydrolase domain-containing protein lpqK lpqM (requalified) — neutral zinc metallopeptidase lpqM espI (family_assigned) — MinD/ParA family protein espI esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 lpqY (family_assigned) — trehalose ABC transporter substrate-binding protei lpqY sugA (family_assigned) — trehalose ABC transporter permease SugA sugA sugC (family_assigned) — trehalose ABC transporter ATP-binding protein SugC sugC sugB (family_assigned) — trehalose ABC transporter permease SugB sugB Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c lpqZ (family_assigned) — glycine betaine ABC transporter substrate-binding lpqZ arfA (family_assigned) — peptidoglycan-binding protein ArfA arfA arfB (family_assigned) — hypothetical protein arfB PE_PGRS30 (family_assigned) — PE-PGRS family protein PE_PGRS30 PE_PGRS30 Rv0898c (family_assigned) — DUF2630 family protein Rv0898c PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.