MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1195 · 40 genes shown · anchor PPE18 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE13 (family_assigned) — PE family protein PE13 PE13 PPE18 (family_assigned) — PPE family protein PPE18 PPE18 esxK (requalified) — type VII secretion system ESX-5 protein EsxJ esxK esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL PE_PGRS11 (family_assigned) — PE-PGRS family protein PE_PGRS11 PE_PGRS11 Rv0485 (family_assigned) — transcriptional regulator Rv0485 PPE20 (family_assigned) — PPE family protein PPE20 PPE20 PE15 (family_assigned) — PE family protein PE15 PE15 PPE2 (family_assigned) — PPE family protein PPE2 PPE2 esxV (requalified) — ESAT-6 like protein EsxV esxV esxW (requalified) — type VII secretion system protein EsxW esxW esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP esxN (requalified) — ESAT-6 like protein EsxN esxN esxO (requalified) — type VII secretion system effector EsxO esxO esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 csm5 (requalified) — type III-A CRISPR-associated RAMP protein Csm5 csm5 Rv1004c (family_assigned) — hypothetical protein Rv1004c Rv0484c (family_assigned) — SDR family oxidoreductase Rv0484c mshA (requalified) — D-inositol-3-phosphate glycosyltransferase mshA Rv0487 (family_assigned) — YbjN domain-containing protein Rv0487 gpm1 (requalified) — 2,3-bisphosphoglycerate-dependent phosphoglycerate gpm1 senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 regX3 (requalified) — two component sensory transduction protein RegX regX3 pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF pyrC (requalified) — dihydroorotase pyrC pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB Rv1382 (requalified) — transporter Rv1382 carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA cobQ1 (requalified) — cobyric acid synthase cobQ1 pirG (requalified) — exported repetitive protein pirG eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0479c (family_assigned) — DUF2993 domain-containing protein Rv0479c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.