MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1183 · 46 genes shown · anchor papA3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmpL10 (requalified) — RND transporter MmpL10 mmpL10 papA3 (requalified) — acyltransferase PapA3 papA3 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mmpL8 (requalified) — sulfolipid-1 RND transporter MmpL8 mmpL8 chp2 (requalified) — diacyltrehalose acyltransferase Chp2 chp2 Rv3492c (requalified) — Mce associated protein Rv3492c pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA1 (requalified) — acyltransferase PapA1 papA1 Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c Rv1145 (requalified) — transmembrane transport protein Rv1145 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv3479 (requalified) — transmembrane protein Rv3479 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas fas (requalified) — fatty acid synthase fas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB chp1 (requalified) — sulfolipid-1 biosynthesis membrane-anchored acyltr chp1 fadD21 (requalified) — fatty-acid--AMP ligase FAAL21/FadD21 fadD21 lipF (requalified) — carboxylesterase LipF lipF mce4D (family_assigned) — virulence factor Mce family protein mce4D lprN (family_assigned) — Mce family lipoprotein LprN lprN mce4F (family_assigned) — virulence factor Mce family protein mce4F Rv3493c (requalified) — mammalian cell entry protein Rv3493c mce4A (family_assigned) — Mce family protein Mce4A mce4A mce4C (family_assigned) — virulence factor Mce family protein mce4C pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 pks12 (requalified) — type I polyketide synthase pks12 mmpL5 (requalified) — siderophore RND transporter MmpL5 mmpL5 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 mmpL9 (requalified) — RND transporter MmpL9 mmpL9 mmpL2 (requalified) — RND transporter MmpL2 mmpL2 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mmpL1 (requalified) — RND transporter MmpL1 mmpL1 Rv1146 (requalified) — transmembrane transport protein Rv1146 rslA (requalified) — anti-sigma-L factor RslA rslA mmpL6 (requalified) — transmembrane transport protein MmpL6 mmpL6 Rv1147 (family_assigned) — methyltransferase domain-containing protein Rv1147 atpB (family_assigned) — F0F1 ATP synthase subunit A atpB atpE (family_assigned) — F0F1 ATP synthase subunit C atpE atpF (family_assigned) — F0F1 ATP synthase subunit B atpF atpH (family_assigned) — F0F1 ATP synthase subunit B/delta atpH

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.