MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1100 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1100 (family_assigned) — hypothetical protein Rv1100 Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 Rv1019 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1019 Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv2732c (family_assigned) — hypothetical protein Rv2732c fum (requalified) — class II fumarate hydratase fum Rv1610 (family_assigned) — TIGR02234 family membrane protein Rv1610 Rv3802c (requalified) — phospholipase Rv3802c Rv0358 (requalified) — peptidase M50 Rv0358 Rv0010c (family_assigned) — PH domain-containing protein Rv0010c prrA (requalified) — two-component system response regulator PrrA prrA sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR aftA (requalified) — galactan 5-O-arabinofuranosyltransferase aftA nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ Rv1359 (family_assigned) — transcriptional regulator Rv1359 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv1152 (family_assigned) — GntR family transcriptional regulator Rv1152 Rv0653c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0653c Rv1985c (family_assigned) — ArgP/LysG family DNA-binding transcriptional regul Rv1985c Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c Rv1487 (family_assigned) — NfeD family protein Rv1487 ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv1489 (family_assigned) — hypothetical protein Rv1489 mpa (requalified) — proteasome ATPase mpa lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 miaB (requalified) — tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiot miaB Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv3212 (family_assigned) — hypothetical protein Rv3212 Rv1109c (requalified) — lipid droplet-associated protein Rv1109c sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA frdA (family_assigned) — fumarate reductase (quinol) flavoprotein subunit frdA Rv0248c (family_assigned) — fumarate reductase/succinate dehydrogenase flavopr Rv0248c mdh (requalified) — malate dehydrogenase mdh Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB trpE (requalified) — anthranilate synthase component I trpE trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC bcpB (requalified) — peroxiredoxin BcpB bcpB Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 Rv3843c (family_assigned) — DUF4328 domain-containing protein Rv3843c ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA fbpD (requalified) — MPT51/MPB51 antigen fbpD pks13 (requalified) — polyketide synthase Pks13 pks13

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.