MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0818 · 43 genes shown · anchor mshD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0818 (requalified) — response regulator transcription factor Rv0818 mshD (requalified) — mycothiol synthase mshD Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 tcrY (requalified) — two component sensor kinase TcrY tcrY phoT (family_assigned) — phosphate ABC transporter ATP-binding protein PstB phoT mprB (requalified) — two-component system sensor histidine kinase MprB mprB prrB (requalified) — two-component system sensor histidine kinase PrrB prrB phoR (requalified) — sensory box histidine kinase PhoR phoR Rv0601c (requalified) — two component sensor kinase HK2 Rv0601c lmeA (requalified) — mannan chain length control protein LmeA lmeA mtrB (requalified) — two-component system sensor histidine kinase MtrB mtrB ppk1 (requalified) — RNA degradosome polyphosphate kinase ppk1 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c mshC (requalified) — cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D mshC Rv1998c (family_assigned) — isocitrate lyase/phosphoenolpyruvate mutase family Rv1998c mca (requalified) — mycothiol conjugate amidase Mca mca tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA prrA (requalified) — two-component system response regulator PrrA prrA mtrA (requalified) — two-component system response regulator MtrA mtrA regX3 (requalified) — two component sensory transduction protein RegX regX3 mprA (requalified) — two-component system response regulator MprA mprA trcR (requalified) — two-component system response regulator TrcR trcR kdpE (requalified) — two-component system response regulator KdpE kdpE tcrX (requalified) — two-component system response regulator TcrX tcrX phoP (requalified) — two-component system response regulator PhoP phoP pstA1 (family_assigned) — phosphate ABC transporter permease PstA pstA1 pstC2 (family_assigned) — phosphate ABC transporter permease subunit PstC pstC2 pstA2 (family_assigned) — phosphate ABC transporter permease PstA pstA2 pstC1 (family_assigned) — phosphate ABC transporter permease PstC pstC1 pstS3 (family_assigned) — phosphate ABC transporter substrate-binding lipopr pstS3 pstS2 (family_assigned) — phosphate ABC transporter substrate-binding lipopr pstS2 pepD (requalified) — serine protease PepD pepD Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB thiX (family_assigned) — thioredoxin family protein thiX ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA hbhA (requalified) — heparin-binding hemagglutinin HbhA hbhA eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv2743c (family_assigned) — hypothetical protein Rv2743c lpqB (requalified) — MtrAB system accessory lipoprotein LpqB lpqB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.