MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0779c · 46 genes shown · anchor purC · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0779c (dark) — hypothetical protein Rv0779c purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC ptrBa (family_assigned) — Probable protease II PtrBa [first part] (oligopept ptrBa ptrBb (family_assigned) — Probable protease II PtrBb [second part] (oligopep ptrBb Rv0517 (requalified) — acyltransferase Rv0517 Rv3779 (family_assigned) — DUF6541 family protein Rv3779 Rv0875c (dark) — DUF2771 domain-containing protein Rv0875c Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv1353c (family_assigned) — TetR/AcrR family transcriptional regulator C-termi Rv1353c Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c rsfA (requalified) — anti-sigma-F factor antagonist RsfA rsfA Rv3662c (requalified) — oxidoreductase Rv3662c purD (requalified) — phosphoribosylamine--glycine ligase purD purB (requalified) — adenylosuccinate lyase purB purE (requalified) — 5-(carboxyamino)imidazole ribonucleotide mutase purE purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv0457c (family_assigned) — prolyl oligopeptidase family protein Rv0457c clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 Rv1732c (family_assigned) — thioredoxin family protein Rv1732c clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv0518 (family_assigned) — SGNH/GDSL hydrolase family protein Rv0518 egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE Rv3707c (requalified) — hypothetical protein Rv3707c rfbE (family_assigned) — ABC transporter ATP-binding protein rfbE bpa (requalified) — proteasome activator protein Bpa bpa rfbD (family_assigned) — ABC transporter permease rfbD glfT1 (requalified) — galactofuranosyl transferase GlfT glfT1 Rv3632 (family_assigned) — DUF2304 domain-containing protein Rv3632 Rv0876c (requalified) — MFS transporter Rv0876c Rv0877 (dark) — DUF3027 domain-containing protein Rv0877 Rv1171 (family_assigned) — hypothetical protein Rv1171 prrB (requalified) — two-component system sensor histidine kinase PrrB prrB Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 Rv0188 (requalified) — SPW repeat protein Rv0188 Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c Rv3163c (dark) — DUF58 domain-containing protein Rv3163c Rv3165c (dark) — hypothetical protein Rv3165c moxR3 (family_assigned) — MoxR family ATPase moxR3 Rv3162c (family_assigned) — integral membrane protein Rv3162c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c moeY (family_assigned) — Rv1355c family protein moeY Rv1356c (requalified) — hypothetical protein Rv1356c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.