Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0745 · 45 genes shown · anchor PE_PGRS9 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0745 (family_assigned) — hypothetical protein Rv0745 Rv2891 (family_assigned) — hypothetical protein Rv2891 Rv0648 (requalified) — alpha-mannosidase Rv0648 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 galK (requalified) — galactokinase galK PE_PGRS9 (family_assigned) — PE-PGRS family protein PE_PGRS9 PE_PGRS9 Rv1004c (family_assigned) — hypothetical protein Rv1004c PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PPE5 (family_assigned) — PPE family protein PPE5 PPE5 iniB (requalified) — isoniazid-induced protein IniB iniB PPE56 (family_assigned) — PPE family protein PPE56 PPE56 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 amiC (requalified) — amidase amiC rpsB (requalified) — 30S ribosomal protein S2 rpsB Rv0650 (family_assigned) — ROK family protein Rv0650 fabD2 (requalified) — malonyl CoA-acyl carrier protein transacylase fabD2 Rv1999c (family_assigned) — APC family permease Rv1999c Rv0371c (family_assigned) — NTP transferase domain-containing protein Rv0371c eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 galTa (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTa galTb (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTb Rv1752 (family_assigned) — hypothetical protein Rv1752 bglS (requalified) — beta-glucosidase BglS bglS Rv0743c (family_assigned) — DUF6036 family nucleotidyltransferase Rv0743c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH lppB (family_assigned) — LppA family lipoprotein lppB rplD (requalified) — 50S ribosomal protein L4 rplD ftsY (requalified) — signal recognition particle-docking protein FtsY ftsY rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplW (requalified) — 50S ribosomal protein L23 rplW Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 PPE34 (family_assigned) — PPE family protein PPE34 PPE34 PPE54 (family_assigned) — PPE family protein PPE54 PPE54 PPE6 (family_assigned) — PPE family protein PPE6 PPE6 PPE8 (family_assigned) — PPE family protein PPE8 PPE8

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.