MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0658c · 46 genes shown · anchor eccD1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0658c (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0658c eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 Rv1632c (family_assigned) — DUF402 domain-containing protein Rv1632c Rv1375 (family_assigned) — YcaO-like family protein Rv1375 vapB6 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB6 rsmA (requalified) — anti-sigma-M factor RsmA rsmA esxA (requalified) — ESAT-6 protein EsxA esxA Rv2360c (family_assigned) — hypothetical protein Rv2360c Rv3737 (family_assigned) — threonine/serine exporter family protein Rv3737 Rv3212 (family_assigned) — hypothetical protein Rv3212 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espI (family_assigned) — MinD/ParA family protein espI eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 espB (requalified) — type VII secretion system ESX-1 target EspB espB lpqW (requalified) — lipoarabinomannan biosynthesis protein LpqW lpqW Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv1376 (family_assigned) — TfuA-like protein Rv1376 Rv1863c (family_assigned) — integral membrane protein Rv1863c Rv1140 (family_assigned) — integral membrane protein Rv1140 Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 vapC6 (requalified) — ribonuclease VapC6 vapC6 vapC27 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC27 sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv3909 (dark) — hypothetical protein Rv3909 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ mutT4 (requalified) — NUDIX hydrolase mutT4 trxC (requalified) — thioredoxin trxC trxB2 (requalified) — thioredoxin-disulfide reductase trxB2 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB esxO (requalified) — type VII secretion system effector EsxO esxO esxW (requalified) — type VII secretion system protein EsxW esxW Rv2361c (requalified) — decaprenyl diphosphate synthase Rv2361c recO (requalified) — DNA repair protein RecO recO amiA2 (requalified) — amidase amiA2 Rv0497 (family_assigned) — hypothetical protein Rv0497 Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 Rv3735 (requalified) — adenosine-specific kinase Rv3735 fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.