MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0643c · 46 genes shown · anchor mmaA4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 Rv0448c (dark) — hypothetical protein Rv0448c Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB pks13 (requalified) — polyketide synthase Pks13 pks13 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA Rv0386 (family_assigned) — LuxR family transcriptional regulator Rv0386 Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv0373c (family_assigned) — aerobic carbon-monoxide dehydrogenase large subuni Rv0373c Rv0195 (requalified) — response regulator transcription factor Rv0195 pcaA (requalified) — cyclopropane mycolic acid synthase pcaA hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY mmaA1 (requalified) — mycolic acid methyltransferase MmaA1 mmaA1 lipG (requalified) — lipase/esterase LipG lipG ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK rskA (requalified) — anti-sigma-K factor RskA rskA mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 hadC (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadC hadC Rv0504c (family_assigned) — MaoC family dehydratase N-terminal domain-containi Rv0504c adk (requalified) — adenylate kinase adk rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rplF (requalified) — 50S ribosomal protein L6 rplF mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 fabH (requalified) — beta-ketoacyl-ACP synthase III fabH Rv2434c (requalified) — mechanosensitive ion channel Rv2434c Rv0104 (family_assigned) — cyclic nucleotide-binding domain-containing protei Rv0104 glnQ (family_assigned) — ATP-binding cassette domain-containing protein glnQ Rv0073 (family_assigned) — ATP-binding cassette domain-containing protein Rv0073 Rv3728 (requalified) — MFS transporter Rv3728

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.