Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0623 · 45 genes shown · anchor vapC30 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 vapC28 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC28 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapC36 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC36 vapC34 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC34 Rv0622 (dark) — DUF732 domain-containing protein Rv0622 vapC15 (family_assigned) — PIN domain nuclease vapC15 Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c vapB11 (requalified) — antitoxin VapB11 vapB11 Rv0621 (family_assigned) — membrane protein Rv0621 vapC24 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC24 vapC20 (requalified) — type II toxin-antitoxin system toxin 23S rRNA-spec vapC20 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 parD1 (family_assigned) — type II toxin-antitoxin system ParD family antitox parD1 Rv1395 (family_assigned) — HTH-type transcriptional regulator Rv1395 ethR (family_assigned) — HTH-type transcriptional regulator EthR ethR sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR vapB28 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB28 Rv0609A (dark) — hypothetical protein Rv0609A Rv0607 (dark) — hypothetical protein Rv0607 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapB36 (requalified) — antitoxin VapB36 vapB36 PE_PGRS35 (family_assigned) — PE-PGRS family protein PE_PGRS35 PE_PGRS35 Rv0919 (family_assigned) — GNAT family N-acetyltransferase Rv0919 Rv1742 (family_assigned) — hypothetical protein Rv1742 Rv1739c (family_assigned) — SulP family inorganic anion transporter Rv1739c pknE (requalified) — serine/threonine protein kinase PknE pknE vapB15 (requalified) — antitoxin VapB15 vapB15 Rv2008c (family_assigned) — hypothetical protein Rv2008c vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv2023c (dark) — hypothetical protein Rv2023c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv0332 (family_assigned) — hypothetical protein Rv0332 vapC11 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC11 cobB (requalified) — NAD-dependent protein deacylase cobB Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 galTb (family_assigned) — Probable galactose-1-phosphate uridylyltransferase galTb Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.