MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0519c · 44 genes shown · anchor pks13 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0519c (family_assigned) — membrane protein Rv0519c mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1084 (family_assigned) — thioredoxin domain-containing protein Rv1084 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv0272c (family_assigned) — alpha/beta hydrolase Rv0272c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtE (requalified) — peptide synthetase mbtE irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mca (requalified) — mycothiol conjugate amidase Mca mca Rv1083 (dark) — hypothetical protein Rv1083 Rv1081c (dark) — DUF4307 domain-containing protein Rv1081c Rv1987 (family_assigned) — cellulose-binding protein Rv1987 celA1 (requalified) — cellulase CelA celA1 fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 Rv0274 (family_assigned) — VOC family protein Rv0274 fadE6 (family_assigned) — acyl-CoA dehydrogenase family protein fadE6 Rv0311 (family_assigned) — hypothetical protein Rv0311 Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 Rv0767c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0767c mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0674 (family_assigned) — PaaX family transcriptional regulator C-terminal d Rv0674 trcR (requalified) — two-component system response regulator TrcR trcR moxR3 (family_assigned) — MoxR family ATPase moxR3 mbtI (requalified) — salicylate synthase mbtI entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.