Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0517 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0517 (requalified) — acyltransferase Rv0517 Rv0518 (family_assigned) — SGNH/GDSL hydrolase family protein Rv0518 Rv3779 (family_assigned) — DUF6541 family protein Rv3779 Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE Rv0779c (dark) — hypothetical protein Rv0779c Rv3707c (requalified) — hypothetical protein Rv3707c Rv0875c (dark) — DUF2771 domain-containing protein Rv0875c Rv2828c (family_assigned) — DUF1802 family protein Rv2828c oprA (requalified) — osmosensory protein OprA oprA Rv2825c (dark) — hypothetical protein Rv2825c Rv3906c (requalified) — pullulanase Rv3906c lppW (family_assigned) — hypothetical protein lppW pirG (requalified) — exported repetitive protein pirG Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 rfbE (family_assigned) — ABC transporter ATP-binding protein rfbE bpa (requalified) — proteasome activator protein Bpa bpa rfbD (family_assigned) — ABC transporter permease rfbD glfT1 (requalified) — galactofuranosyl transferase GlfT glfT1 Rv3632 (family_assigned) — DUF2304 domain-containing protein Rv3632 Rv1171 (family_assigned) — hypothetical protein Rv1171 Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 Rv0188 (requalified) — SPW repeat protein Rv0188 Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB spmT (requalified) — sphingomyelinase spmT purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC ptrBa (family_assigned) — Probable protease II PtrBa [first part] (oligopept ptrBa ptrBb (family_assigned) — Probable protease II PtrBb [second part] (oligopep ptrBb ask (requalified) — aspartate kinase ask asd (requalified) — aspartate-semialdehyde dehydrogenase asd lpqF (requalified) — serine hydrolase lpqF Rv2743c (family_assigned) — hypothetical protein Rv2743c Rv0876c (requalified) — MFS transporter Rv0876c Rv0877 (dark) — DUF3027 domain-containing protein Rv0877 prrB (requalified) — two-component system sensor histidine kinase PrrB prrB Rv2828A (dark) — hypothetical protein Rv2828A vapC22 (family_assigned) — PIN domain-containing protein vapC22 vapB22 (family_assigned) — type II toxin-antitoxin system prevent-host-death vapB22 echA16 (requalified) — enoyl-CoA hydratase echA16 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.