MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0514 · 46 genes shown · anchor hemB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0514 (dark) — hypothetical protein Rv0514 hemB (requalified) — porphobilinogen synthase hemB Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 hemA (requalified) — glutamyl-tRNA reductase hemA aroE (requalified) — shikimate dehydrogenase aroE rnhB (requalified) — ribonuclease HII rnhB Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 Rv0515 (family_assigned) — hypothetical protein Rv0515 ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA engA (requalified) — ribosome biogenesis GTPase Der engA hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA Rv0526 (requalified) — thioredoxin Rv0526 Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 gltS (requalified) — glutamate--tRNA ligase gltS aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroB (requalified) — 3-dehydroquinate synthase aroB aroK (requalified) — shikimate kinase AroK aroK mltG (requalified) — endolytic transglycosylase MltG mltG aroD (requalified) — type II 3-dehydroquinate dehydratase aroD Rv2551c (family_assigned) — A24 family peptidase Rv2551c lepB (requalified) — signal peptidase I lepB rplS (requalified) — 50S ribosomal protein L19 rplS dnaN (family_assigned) — DNA polymerase III subunit beta dnaN lppK (family_assigned) — hypothetical protein lppK Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c coaE (requalified) — dephospho-CoA kinase coaE mmpS2 (family_assigned) — MmpS family protein mmpS2 mmpL2 (requalified) — RND transporter MmpL2 mmpL2 nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ Rv0336 (family_assigned) — hypothetical protein Rv0336 Rv1765c (family_assigned) — hypothetical protein Rv1765c Rv1702c (requalified) — HNH endonuclease signature motif containing protei Rv1702c Rv2015c (requalified) — HNH endonuclease signature motif containing protei Rv2015c Rv1128c (family_assigned) — hypothetical protein Rv1128c Rv1945 (requalified) — HNH endonuclease signature motif containing protei Rv1945 cmk (requalified) — (d)CMP kinase cmk

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.