MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0504c · 46 genes shown · anchor hadB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0504c (family_assigned) — MaoC family dehydratase N-terminal domain-containi Rv0504c hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB cmaA2 (requalified) — cyclopropane mycolic acid synthase CmaA2 cmaA2 serB1 (requalified) — phosphoserine phosphatase SerB serB1 icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 Rv2242 (family_assigned) — PucR family transcriptional regulator Rv2242 pepA (family_assigned) — S1C family serine protease pepA fadB (requalified) — fatty oxidation protein FadB fadB marP (requalified) — acid resistance serine protease MarP marP fadE25 (requalified) — acyl-CoA dehydrogenase fadE25 pepD (requalified) — serine protease PepD pepD htrA (requalified) — serine protease HtrA htrA Rv1043c (requalified) — serine protease Rv1043c hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA hadC (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadC hadC adk (requalified) — adenylate kinase adk rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rplF (requalified) — 50S ribosomal protein L6 rplF Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c pks13 (requalified) — polyketide synthase Pks13 pks13 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 serC (requalified) — phosphoserine transaminase serC hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF glyA2 (requalified) — serine hydroxymethyltransferase glyA2 acn (requalified) — iron-regulated aconitate hydratase Acn acn Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c mdh (requalified) — malate dehydrogenase mdh fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD aceE (requalified) — pyruvate dehydrogenase E1 component aceE kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 mpa (requalified) — proteasome ATPase mpa treS (requalified) — maltose alpha-D-glucosyltransferase treS glpK (requalified) — glycerol kinase GlpK glpK mak (requalified) — maltokinase mak mec (requalified) — CysO-cysteine peptidase mec prcA (family_assigned) — proteasome subunit alpha prcA fadA (requalified) — acetyl-CoA C-acetyltransferase fadA fadA2 (requalified) — acetyl-CoA C-acetyltransferase fadA2 fadA4 (requalified) — acetyl-CoA acetyltransferase fadA4 fadA6 (requalified) — acetyl-CoA C-acetyltransferase fadA6

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.