MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0503c · 46 genes shown · anchor serB1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
cmaA2 (requalified) — cyclopropane mycolic acid synthase CmaA2 cmaA2 Rv0504c (family_assigned) — MaoC family dehydratase N-terminal domain-containi Rv0504c serB1 (requalified) — phosphoserine phosphatase SerB serB1 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c pks13 (requalified) — polyketide synthase Pks13 pks13 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 inhA (requalified) — NADH-dependent enoyl-ACP reductase InhA inhA fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu Rv3787c (requalified) — class I SAM-dependent methyltransferase Rv3787c hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 Rv2242 (family_assigned) — PucR family transcriptional regulator Rv2242 pepA (family_assigned) — S1C family serine protease pepA Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 serC (requalified) — phosphoserine transaminase serC hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF glyA2 (requalified) — serine hydroxymethyltransferase glyA2 ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv0448c (dark) — hypothetical protein Rv0448c cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas hemZ (requalified) — ferrochelatase hemZ sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM fabH (requalified) — beta-ketoacyl-ACP synthase III fabH mbtE (requalified) — peptide synthetase mbtE Rv3802c (requalified) — phospholipase Rv3802c mbtF (requalified) — peptide synthetase mbtF efpA (requalified) — multidrug efflux MFS transporter EfpA efpA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.