MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0448c · 37 genes shown · anchor ufaA1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0448c (dark) — hypothetical protein Rv0448c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK rskA (requalified) — anti-sigma-K factor RskA rskA mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 Rv3720 (requalified) — fatty acid synthase Rv3720 mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp dipZ (requalified) — integral membrane C-type cytochrome biogenesis pro dipZ nuoD (family_assigned) — NADH dehydrogenase (quinone) subunit D nuoD Rv2876 (requalified) — transmembrane protein Rv2876 nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 lppX (requalified) — LppX_LprAFG lipoprotein lppX Rv0452 (family_assigned) — TetR family transcriptional regulator Rv0452 iunH (requalified) — nucleoside hydrolase IunH iunH pks13 (requalified) — polyketide synthase Pks13 pks13 Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c Rv3254 (requalified) — oxidoreductase Rv3254 Rv3719 (family_assigned) — hypothetical protein Rv3719 Rv3718c (family_assigned) — SRPBCC family protein Rv3718c guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv3502c (requalified) — 3-oxoacyl-ACP reductase Rv3502c mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.