MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0447c · 42 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c Rv0448c (dark) — hypothetical protein Rv0448c Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv3840 (family_assigned) — transcriptional regulator Rv3840 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr rskA (requalified) — anti-sigma-K factor RskA rskA mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 cobB (requalified) — NAD-dependent protein deacylase cobB tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c Rv1359 (family_assigned) — transcriptional regulator Rv1359 embR (requalified) — response regulator transcription factor EmbR embR Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB mftC (requalified) — mycofactocin radical SAM maturase mftC Rv0690c (family_assigned) — DUF2332 domain-containing protein Rv0690c Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c sigI (requalified) — RNA polymerase sigma factor SigI sigI Rv2282c (family_assigned) — LysR family transcriptional regulator Rv2282c Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 lppX (requalified) — LppX_LprAFG lipoprotein lppX

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.