Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0446c · 46 genes shown · anchor ufaA1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c Rv0448c (dark) — hypothetical protein Rv0448c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK rskA (requalified) — anti-sigma-K factor RskA rskA mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 Rv0885 (requalified) — diiron oxygenase Rv0885 Rv3355c (dark) — DUF3017 domain-containing protein Rv3355c Rv1855c (requalified) — LLM class F420-dependent oxidoreductase Rv1855c Rv3346c (dark) — DUF3017 domain-containing protein Rv3346c Rv3049c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv3049c cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 lppX (requalified) — LppX_LprAFG lipoprotein lppX Rv0452 (family_assigned) — TetR family transcriptional regulator Rv0452 fprB (requalified) — FAD-dependent oxidoreductase fprB serC (requalified) — phosphoserine transaminase serC Rv3338 (family_assigned) — Conserved hypothetical protein Rv3338 Rv3249c (family_assigned) — TetR family transcriptional regulator Rv3249c sepH (requalified) — septation protein SepH sepH Rv0464c (family_assigned) — carboxymuconolactone decarboxylase family protein Rv0464c folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD Rv3359 (requalified) — NADH:flavin oxidoreductase Rv3359 relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ relK (family_assigned) — Txe/YoeB family addiction module toxin relK lprD (family_assigned) — hypothetical protein lprD Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv1856c (family_assigned) — SDR family oxidoreductase Rv1856c Rv3178 (requalified) — nitroreductase Rv3178 Rv3520c (requalified) — coenzyme F420-dependent oxidoreductase Rv3520c fbiA (requalified) — 2-phospho-L-lactate transferase fbiA ddn (requalified) — deazaflavin-dependent nitroreductase Ddn ddn Rv3093c (requalified) — LLM class F420-dependent oxidoreductase Rv3093c aftC (requalified) — arabinofuranan 3-O-arabinosyltransferase aftC Rv1476 (family_assigned) — DUF6676 family protein Rv1476 Rv3035 (family_assigned) — hypothetical protein Rv3035

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.