MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0444c · 46 genes shown · anchor sigK · open gene page → · ← back to 1 hop

Evidence: Min score 0
rskA (requalified) — anti-sigma-K factor RskA rskA sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK Rv0448c (dark) — hypothetical protein Rv0448c Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv2113 (family_assigned) — integral membrane protein Rv2113 Rv3909 (dark) — hypothetical protein Rv3909 Rv3835 (family_assigned) — septum formation family protein Rv3835 ureD (requalified) — urease accessory protein UreD ureD Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 pbpB (requalified) — D%2CD-transpeptidase PbpB pbpB ftsQ (requalified) — cell division protein FtsQ ftsQ rsmH (requalified) — 16S rRNA (cytosine(1402)-N(4))-methyltransferase R rsmH mraZ (requalified) — division/cell wall cluster transcriptional repress mraZ Rv0539 (requalified) — dolichyl-phosphate sugar synthase Rv0539 Rv0540 (family_assigned) — DUF2064 domain-containing protein Rv0540 Rv1775 (family_assigned) — hypothetical protein Rv1775 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 embR (requalified) — response regulator transcription factor EmbR embR mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv2114 (dark) — hypothetical protein Rv2114 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ mutT4 (requalified) — NUDIX hydrolase mutT4 rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv3906c (requalified) — pullulanase Rv3906c Rv3836 (family_assigned) — metallopeptidase family protein Rv3836 serS (requalified) — serine--tRNA ligase serS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.