Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0300 · 46 genes shown · anchor vapC2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 vapC2 (family_assigned) — PIN domain nuclease vapC2 Rv0299 (requalified) — toxin-antitoxin system toxin Rv0299 Rv0298 (family_assigned) — ribbon-helix-helix protein%2C CopG family Rv0298 Rv0302 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0302 Rv0303 (requalified) — protochlorophyllide reductase Rv0303 vapC15 (family_assigned) — PIN domain nuclease vapC15 vapC5 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC5 Rv0229c (family_assigned) — PIN domain nuclease Rv0229c vapC11 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC11 vapC10 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC10 vapC8 (family_assigned) — PIN domain-containing protein vapC8 vapC6 (requalified) — ribonuclease VapC6 vapC6 PE_PGRS5 (family_assigned) — PE-PGRS family protein PE_PGRS5 PE_PGRS5 Rv1534 (family_assigned) — TetR family transcriptional regulator Rv1534 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 fas (requalified) — fatty acid synthase fas Rv0296c (requalified) — sulfatase Rv0296c Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 htpG (requalified) — molecular chaperone HtpG htpG Rv0073 (family_assigned) — ATP-binding cassette domain-containing protein Rv0073 vapB15 (requalified) — antitoxin VapB15 vapB15 vapB11 (requalified) — antitoxin VapB11 vapB11 Rv2008c (family_assigned) — hypothetical protein Rv2008c vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 vapB4 (requalified) — type II toxin-antitoxin system antitoxin VapB4 vapB4 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv0625c (family_assigned) — TVP38/TMEM64 family protein Rv0625c vapC47 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC47 Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c php (requalified) — phosphotriesterase-related protein php fadE4 (family_assigned) — acyl-CoA dehydrogenase family protein fadE4 vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 chaA (requalified) — calcium:proton antiporter chaA vapB41 (requalified) — antitoxin VapB41 vapB41 Rv3677c (requalified) — MBL fold metallo-hydrolase Rv3677c Rv2531c (requalified) — amino acid decarboxylase Rv2531c ilvA (requalified) — threonine ammonia-lyase ilvA vapB10 (family_assigned) — CopG family transcriptional regulator vapB10 nlhH (family_assigned) — alpha/beta hydrolase nlhH lipI (family_assigned) — alpha/beta hydrolase lipI Rv0611c (family_assigned) — DUF4926 domain-containing protein Rv0611c vapC20 (requalified) — type II toxin-antitoxin system toxin 23S rRNA-spec vapC20

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.