MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0251c · 46 genes shown · anchor nirD · open gene page → · ← back to 1 hop

Evidence: Min score 0
hsp (requalified) — stress-responsive chaperone Acr2 hsp clpB (requalified) — chaperone protein ClpB clpB clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 clpC2 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC2 nirD (family_assigned) — nitrite reductase small subunit NirD nirD htpG (requalified) — molecular chaperone HtpG htpG fxsA (family_assigned) — FxsA family protein fxsA Rv0250c (family_assigned) — hypothetical protein Rv0250c dnaK (requalified) — molecular chaperone DnaK dnaK Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv2004c (family_assigned) — AAA family ATPase Rv2004c grpE (requalified) — nucleotide exchange factor GrpE grpE clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 Rv2668 (family_assigned) — hypothetical protein Rv2668 nirB (family_assigned) — nitrite reductase large subunit NirB nirB narH (family_assigned) — nitrate reductase subunit beta narH narG (family_assigned) — nitrate reductase subunit alpha narG narI (family_assigned) — respiratory nitrate reductase subunit gamma narI narX (family_assigned) — respiratory nitrate reductase subunit gamma narX narU (family_assigned) — NarK family nitrate/nitrite MFS transporter narU dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 Rv2052c (requalified) — amidohydrolase Rv2052c ppm1 (requalified) — apolipoprotein N-acyltransferase ppm1 Rv2054 (family_assigned) — dienelactone hydrolase family protein Rv2054 sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB pepD (requalified) — serine protease PepD pepD Rv0249c (family_assigned) — succinate dehydrogenase membrane anchor subunit Rv0249c Rv0248c (family_assigned) — fumarate reductase/succinate dehydrogenase flavopr Rv0248c Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c Rv0431 (requalified) — tuberculin-like peptide Rv0431 Rv3415c (family_assigned) — hypothetical protein Rv3415c lppL (family_assigned) — hypothetical protein lppL hspR (family_assigned) — heat shock transcriptional regulator HspR hspR groEL1 (requalified) — chaperonin GroEL groEL1 groEL2 (requalified) — chaperonin GroEL groEL2 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 pirG (requalified) — exported repetitive protein pirG Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv2005c (requalified) — universal stress protein Rv2005c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.