MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0249c · 45 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0249c (family_assigned) — succinate dehydrogenase membrane anchor subunit Rv0249c Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c Rv0248c (family_assigned) — fumarate reductase/succinate dehydrogenase flavopr Rv0248c Rv0250c (family_assigned) — hypothetical protein Rv0250c sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB frdB (family_assigned) — succinate dehydrogenase iron-sulfur subunit frdB sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA frdA (family_assigned) — fumarate reductase (quinol) flavoprotein subunit frdA rsfB (family_assigned) — STAS domain-containing protein rsfB kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD Rv1817 (family_assigned) — FAD-binding protein Rv1817 Rv3818 (requalified) — MBL fold metallo-hydrolase Rv3818 hsp (requalified) — stress-responsive chaperone Acr2 hsp sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC sdhD (family_assigned) — succinate dehydrogenase hydrophobic membrane ancho sdhD Rv0431 (requalified) — tuberculin-like peptide Rv0431 Rv3415c (family_assigned) — hypothetical protein Rv3415c lppL (family_assigned) — hypothetical protein lppL sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC frdD (family_assigned) — fumarate reductase subunit FrdD frdD frdC (family_assigned) — fumarate reductase subunit C frdC fum (requalified) — class II fumarate hydratase fum Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c rsbW (requalified) — anti-sigma B factor RsbW rsbW Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC mkl (family_assigned) — ABC transporter ATP-binding protein mkl Rv0258c (requalified) — hypothetical protein Rv0258c Rv3538 (requalified) — dehydrogenase Rv3538 kshA (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase subunit KshA kshA Rv0760c (family_assigned) — ketosteroid isomerase family protein Rv0760c kshB (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase reductase subuni kshB Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c Rv3819 (dark) — hypothetical protein Rv3819 Rv0688 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0688 nirB (family_assigned) — nitrite reductase large subunit NirB nirB Rv1869c (requalified) — FAD-dependent oxidoreductase Rv1869c hemD (requalified) — uroporphyrin-III C-methyltransferase hemD cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG clpB (requalified) — chaperone protein ClpB clpB clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 clpC2 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC2 nirD (family_assigned) — nitrite reductase small subunit NirD nirD htpG (requalified) — molecular chaperone HtpG htpG fxsA (family_assigned) — FxsA family protein fxsA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.