MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0191 · 46 genes shown · anchor ilvD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0191 (family_assigned) — Rv0191 family MFS efflux transporter Rv0191 Rv0190 (family_assigned) — metal-sensitive transcriptional regulator Rv0190 Rv0192 (family_assigned) — hypothetical protein Rv0192 ilvD (requalified) — dihydroxy-acid dehydratase ilvD Rv1667c (family_assigned) — Probable second part of macrolide-transport ATP-bi Rv1667c proZ (family_assigned) — glycine betaine/carnitine/choline/L-proline ABC tr proZ pdxH (requalified) — pyridoxamine 5'-phosphate oxidase pdxH Rv3008 (family_assigned) — MgtC/SapB family protein Rv3008 panD (requalified) — aspartate 1-decarboxylase panD rpsA (requalified) — 30S ribosomal protein S1 rpsA Rv3675 (dark) — hypothetical protein Rv3675 mscR (requalified) — S-(hydroxymethyl)mycothiol dehydrogenase mscR adhD (requalified) — NDMA-dependent alcohol dehydrogenase adhD adhB (requalified) — alcohol dehydrogenase B adhB adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1 Rv3015c (requalified) — methionine synthase Rv3015c dacB1 (requalified) — D-alanyl-D-alanine carboxypeptidase DacB1 dacB1 dacB2 (family_assigned) — penicillin-binding protein DacB2 dacB2 ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 ponA1 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA1 ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvE (requalified) — branched-chain amino acid aminotransferase ilvE leuA (requalified) — 2-isopropylmalate synthase leuA ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC Rv1668c (family_assigned) — Probable first part of macrolide-transport ATP-bin Rv1668c cyp139 (requalified) — cytochrome P450 cyp139 rplU (requalified) — 50S ribosomal protein L21 rplU rplO (requalified) — 50S ribosomal protein L15 rplO rpsO (requalified) — 30S ribosomal protein S15 rpsO rplM (requalified) — 50S ribosomal protein L13 rplM proV (family_assigned) — glycine betaine/L-proline ABC transporter ATP-bind proV proX (family_assigned) — glycine betaine/carnitine/choline/L-proline ABC tr proX proW (family_assigned) — glycine betaine/carnitine/choline/L-proline ABC tr proW Rv3755c (family_assigned) — putative glycolipid-binding domain-containing prot Rv3755c Rv3760 (family_assigned) — membrane protein Rv3760 lpqZ (family_assigned) — glycine betaine ABC transporter substrate-binding lpqZ snzP (family_assigned) — pyridoxal 5'-phosphate synthase lyase subunit PdxS snzP snoP (family_assigned) — pyridoxal 5'-phosphate synthase glutaminase subuni snoP pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA Rv0887c (family_assigned) — VOC family protein Rv0887c Rv1624c (family_assigned) — HdeD family acid-resistance protein Rv1624c Rv3007c (family_assigned) — flavin reductase family protein Rv3007c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.