MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0189c · 29 genes shown · anchor ilvC · open gene page → · ← back to 1 hop

Evidence: Min score 0
ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvE (requalified) — branched-chain amino acid aminotransferase ilvE leuA (requalified) — 2-isopropylmalate synthase leuA ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD leuB (requalified) — 3-isopropylmalate dehydrogenase leuB ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvA (requalified) — threonine ammonia-lyase ilvA ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX metB (requalified) — cystathionine gamma-synthase metB gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 argJ (requalified) — bifunctional glutamate N-acetyltransferase/amino-a argJ gdh (requalified) — NAD-glutamate dehydrogenase gdh ald (requalified) — alanine dehydrogenase ald panC (requalified) — pantoate--beta-alanine ligase panC panD (requalified) — aspartate 1-decarboxylase panD Rv2573 (requalified) — 2-dehydropantoate 2-reductase Rv2573 Rv2226 (family_assigned) — CYTH and CHAD domain-containing protein Rv2226 serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 thrC (requalified) — threonine synthase thrC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.