MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0140 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0140 (family_assigned) — DUF427 domain-containing protein Rv0140 Rv0139 (family_assigned) — NAD-dependent epimerase/dehydratase family protein Rv0139 Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 msrA (requalified) — peptide-methionine (S)-S-oxide reductase MsrA msrA egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c Rv0569 (family_assigned) — DUF1918 domain-containing protein Rv0569 Rv0145 (requalified) — class I SAM-dependent methyltransferase Rv0145 Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 Rv0274 (family_assigned) — VOC family protein Rv0274 Rv0111 (family_assigned) — acyltransferase family protein Rv0111 atsA (requalified) — arylsulfatase AtsA atsA Rv1366 (family_assigned) — GTP pyrophosphokinase family protein Rv1366 rpsS (requalified) — 30S ribosomal protein S19 rpsS rpsL (requalified) — 30S ribosomal protein S12 rpsL rpsQ (requalified) — 30S ribosomal protein S17 rpsQ Rv1874 (family_assigned) — hypothetical protein Rv1874 Rv0272c (family_assigned) — alpha/beta hydrolase Rv0272c Rv3906c (requalified) — pullulanase Rv3906c msrB (requalified) — peptide-methionine (R)-S-oxide reductase MsrB msrB dipZ (requalified) — integral membrane C-type cytochrome biogenesis pro dipZ thiX (family_assigned) — thioredoxin family protein thiX mpt53 (requalified) — protein disulfide oxidoreductase mpt53 Rv0526 (requalified) — thioredoxin Rv0526 Rv3673c (family_assigned) — membrane-anchored thioredoxin-like protein Rv3673c etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE hisD (requalified) — histidinol dehydrogenase hisD Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 rpiB (requalified) — ribose-5-phosphate isomerase B rpiB Rv3463 (requalified) — LLM class F420-dependent oxidoreductase Rv3463 Rv2464c (family_assigned) — Fpg/Nei family DNA glycosylase Rv2464c mshD (requalified) — mycothiol synthase mshD mca (requalified) — mycothiol conjugate amidase Mca mca mshB (requalified) — N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D- mshB devS (requalified) — two-component system sensor histidine kinase DevS devS devR (requalified) — two-component system response regulator DevR devR nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ Rv2005c (requalified) — universal stress protein Rv2005c narX (family_assigned) — respiratory nitrate reductase subunit gamma narX cyp135B1 (requalified) — cytochrome P450 cyp135B1 Rv0146 (requalified) — class I SAM-dependent methyltransferase Rv0146 Rv0144 (family_assigned) — transcriptional regulator Rv0144 Rv0148 (family_assigned) — SDR family oxidoreductase Rv0148

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.