MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0066c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c acn (requalified) — iron-regulated aconitate hydratase Acn acn icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 mdh (requalified) — malate dehydrogenase mdh purB (requalified) — adenylosuccinate lyase purB gdh (requalified) — NAD-glutamate dehydrogenase gdh gabD2 (requalified) — succinic semialdehyde dehydrogenase gabD2 gabD1 (requalified) — succinate-semialdehyde dehydrogenase gabD1 nadB (requalified) — L-aspartate oxidase nadB aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC gltD (family_assigned) — glutamate synthase subunit beta gltD aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC mobA (requalified) — molybdenum cofactor guanylyltransferase mobA pykA (requalified) — pyruvate kinase pykA prpC (requalified) — 2-methylcitrate synthase prpC citA (requalified) — citrate synthase 2 citA gltA2 (requalified) — citrate synthase gltA2 icl1 (requalified) — isocitrate lyase icl1 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c fum (requalified) — class II fumarate hydratase fum mez (requalified) — NAD-dependent malic enzyme mez pca (requalified) — pyruvate carboxylase pca purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purA (requalified) — adenylosuccinate synthase purA apt (requalified) — adenine phosphoribosyltransferase apt adk (requalified) — adenylate kinase adk fas (requalified) — fatty acid synthase fas Rv2475c (family_assigned) — thioesterase family protein Rv2475c rocA (requalified) — L-glutamate gamma-semialdehyde dehydrogenase rocA garA (requalified) — glycogen accumulation regulator GarA garA glnA1 (requalified) — type I glutamate--ammonia ligase glnA1 gabT (requalified) — 4-aminobutyrate--2-oxoglutarate transaminase gabT sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA Rv0248c (family_assigned) — fumarate reductase/succinate dehydrogenase flavopr Rv0248c sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c nadA (requalified) — quinolinate synthetase A nadA nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC ansA (requalified) — asparaginase ansA pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.