MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0022c · 34 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0023 (family_assigned) — helix-turn-helix transcriptional regulator Rv0023 Rv0025 (dark) — DUF4226 domain-containing protein Rv0025 Rv0027 (family_assigned) — ESX-1 secretion-associated protein Rv0027 Rv0028 (family_assigned) — DUF2694 domain-containing protein Rv0028 Rv0024 (family_assigned) — C40 family peptidase Rv0024 Rv0021c (family_assigned) — nitronate monooxygenase family protein Rv0021c eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv0026 (dark) — hypothetical protein Rv0026 esxT (family_assigned) — WXG100 family type VII secretion target esxT Rv3196 (family_assigned) — hypothetical protein Rv3196 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 Rv0029 (dark) — DUF5631 domain-containing protein Rv0029 ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA ripC (requalified) — peptidoglycan hydrolase RipC ripC Rv2781c (requalified) — nitronate monooxygenase Rv2781c narU (family_assigned) — NarK family nitrate/nitrite MFS transporter narU narK3 (requalified) — nitrate/nitrite transporter narK3 narK2 (requalified) — nitrate transporter NarK narK2 narK1 (requalified) — nitrate/nitrite transporter narK1 narI (family_assigned) — respiratory nitrate reductase subunit gamma narI esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.