ncRv10467 MTB000109

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

558815–558884 (+ strand), 70 nt, on H37Rv (NC_000962.3). Intergenic (no overlapping coding sequence). Upstream neighbour Rv0467 (2 bp). Downstream neighbour Rv0468 (11 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites47
Variants reaching 0.1 % of genomes 1
Carriers of the most widespread variant195

Coverage control

Variant density inside this RNA: 67.1 sites/100 bp, versus 60.5 in the flanking ±500 bp (GC 58.6 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

82.9 % of bases are paired in the minimum-free-energy fold (58 paired, 12 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

Supported by sRNA-Seq in H37Rv (see DeJesus et al. 2017)

Sources

← all RNAs