B55 MTB000052

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

704187–704247 (+ strand), 61 nt, on H37Rv (NC_000962.3). Intergenic (no overlapping coding sequence). Upstream neighbour Rv0609A (130 bp). Downstream neighbour Rv0610c (505 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites61
Variants reaching 0.1 % of genomes 2
Carriers of the most widespread variant169

Coverage control

Variant density inside this RNA: 100.0 sites/100 bp, versus 77.1 in the flanking ±500 bp (GC 70.5 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

75.4 % of bases are paired in the minimum-free-energy fold (46 paired, 15 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

B55, putative small regulatory RNA (See Arnvig and Young, 2009). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007).

Sources

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