MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3905c · 46 genes shown · anchor esxE · open gene page → · ← back to 1 hop

Evidence: Min score 0
esxF (requalified) — pore-forming CpnT exporter EsxF esxF esxE (requalified) — ESAT-6 like protein EsxE esxE cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT ift (requalified) — necrotizing toxin immunity factor IFT ift Rv3906c (requalified) — pullulanase Rv3906c pcnA (requalified) — poly(A) polymerase PcnA pcnA esxG (requalified) — type VII secretion system protein EsxG esxG esxS (requalified) — ESAT-6 like protein EsxS esxS eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 ftsK (requalified) — DNA translocase FtsK ftsK sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM esxT (family_assigned) — WXG100 family type VII secretion target esxT eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ Rv3909 (dark) — hypothetical protein Rv3909 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB mutT4 (requalified) — NUDIX hydrolase mutT4 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 esxH (requalified) — type VII secretion system effector EsxH esxH espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 esxR (family_assigned) — WXG100 family type VII secretion target esxR esxQ (requalified) — type VII secretion system ESX-3 effector EsxQ esxQ PPE4 (family_assigned) — PPE family protein PPE4 PPE4 PPE46 (family_assigned) — PPE family protein PPE46 PPE46 esxV (requalified) — ESAT-6 like protein EsxV esxV esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 parB (family_assigned) — ParB/RepB/Spo0J family partition protein parB parA (requalified) — chromosome partitioning protein ParA parA Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 Rv1708 (requalified) — initiation inhibitor protein Rv1708

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.