MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3902c · 46 genes shown · anchor esxE · open gene page → · ← back to 1 hop

Evidence: Min score 0
ift (requalified) — necrotizing toxin immunity factor IFT ift cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 Rv3906c (requalified) — pullulanase Rv3906c pcnA (requalified) — poly(A) polymerase PcnA pcnA eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 Rv3896c (requalified) — transglycosylase Rv3896c PE2 (family_assigned) — PE family protein PE2 PE2 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c esxG (requalified) — type VII secretion system protein EsxG esxG eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 Rv3900c (family_assigned) — hypothetical protein Rv3900c Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 Rv2086 (family_assigned) — hypothetical protein Rv2086 Rv2083 (dark) — hypothetical protein Rv2083 Rv2305 (family_assigned) — hypothetical protein Rv2305 Rv2084 (dark) — hypothetical protein Rv2084 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ Rv3909 (dark) — hypothetical protein Rv3909 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB mutT4 (requalified) — NUDIX hydrolase mutT4 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 glpK (requalified) — glycerol kinase GlpK glpK mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 Rv2633c (requalified) — non-heme di-iron catalase Rv2633c Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv1733c (family_assigned) — hypothetical protein Rv1733c Rv3786c (family_assigned) — peptidoglycan DD-metalloendopeptidase family prote Rv3786c PE1 (family_assigned) — PE family protein PE1 PE1 ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 PE25 (family_assigned) — PE family protein PE25 PE25

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.