MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3839 · 46 genes shown · anchor pheA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3839 (requalified) — DUF2470 domain-containing protein Rv3839 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA PPE37 (family_assigned) — PPE family protein PPE37 PPE37 pheA (requalified) — prephenate dehydratase pheA Rv3837c (family_assigned) — histidine phosphatase family protein Rv3837c Rv0010c (family_assigned) — PH domain-containing protein Rv0010c Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv3212 (family_assigned) — hypothetical protein Rv3212 cfp6 (requalified) — low molecular weight protein antigen 6 cfp6 cei (requalified) — envelope integrity protein Cei cei Rv1109c (requalified) — lipid droplet-associated protein Rv1109c lppL (family_assigned) — hypothetical protein lppL mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtI (requalified) — salicylate synthase mbtI pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisG (requalified) — ATP phosphoribosyltransferase hisG Rv2120c (family_assigned) — glycine zipper 2TM domain-containing protein Rv2120c irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA tyrA (requalified) — prephenate dehydrogenase TyrA tyrA Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c cobC (requalified) — aminotransferase cobC hisC2 (requalified) — histidinol-phosphate transaminase hisC2 hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 htpX (requalified) — zinc metalloprotease HtpX htpX pepD (requalified) — serine protease PepD pepD cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ crgA (requalified) — cell division protein CrgA crgA lppM (requalified) — lipoprotein LppM lppM Rv1100 (family_assigned) — hypothetical protein Rv1100 cobB (requalified) — NAD-dependent protein deacylase cobB Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c miaB (requalified) — tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiot miaB Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv3850 (family_assigned) — DUF6474 family protein Rv3850 rhlE (requalified) — DEAD/DEAH box helicase rhlE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.