MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3826 · 38 genes shown · anchor mbtE · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD23 (requalified) — long-chain-fatty-acid--CoA ligase FadD23 fadD23 mbtE (requalified) — peptide synthetase mbtE pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtF (requalified) — peptide synthetase mbtF nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp pks15 (requalified) — polyketide synthase pks15 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks6 (requalified) — membrane bound polyketide synthase pks6 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks12 (requalified) — type I polyketide synthase pks12 papA1 (requalified) — acyltransferase PapA1 papA1 mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD pks13 (requalified) — polyketide synthase Pks13 pks13 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 pks1 (requalified) — polyketide synthase pks1 pks17 (requalified) — polyketide synthase pks17 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD papA3 (requalified) — acyltransferase PapA3 papA3 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 fadD30 (requalified) — long-chain-fatty-acid--AMP ligase FadD30 fadD30 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.