MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3824c · 37 genes shown · anchor pks2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
papA1 (requalified) — acyltransferase PapA1 papA1 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mmpL8 (requalified) — sulfolipid-1 RND transporter MmpL8 mmpL8 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH pks1 (requalified) — polyketide synthase pks1 pks7 (requalified) — type I polyketide synthase pks7 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mmpL10 (requalified) — RND transporter MmpL10 mmpL10 Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 Rv1145 (requalified) — transmembrane transport protein Rv1145 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtE (requalified) — peptide synthetase mbtE mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks17 (requalified) — polyketide synthase pks17 ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.