MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3800c · 36 genes shown · anchor mbtB · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks17 (requalified) — polyketide synthase pks17 mbtE (requalified) — peptide synthetase mbtE pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtC (requalified) — polyketide synthetase MbtC mbtC pks7 (requalified) — type I polyketide synthase pks7 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 Rv3802c (requalified) — phospholipase Rv3802c efpA (requalified) — multidrug efflux MFS transporter EfpA efpA accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 accA2 (family_assigned) — biotin carboxylase N-terminal domain-containing pr accA2 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB pks12 (requalified) — type I polyketide synthase pks12 pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks15 (requalified) — polyketide synthase pks15 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC papA1 (requalified) — acyltransferase PapA1 papA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.