MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3777 · 46 genes shown · anchor pks3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3777 (requalified) — oxidoreductase Rv3777 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 mbtC (requalified) — polyketide synthetase MbtC mbtC pks15 (requalified) — polyketide synthase pks15 pks9 (requalified) — type I polyketide synthase pks9 pks17 (requalified) — polyketide synthase pks17 Rv3776 (family_assigned) — hypothetical protein Rv3776 echA21 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA21 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks6 (requalified) — membrane bound polyketide synthase pks6 lipE (requalified) — lipase LipE lipE sigG (family_assigned) — sigma-70 family RNA polymerase sigma factor SigG sigG ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 pks1 (requalified) — polyketide synthase pks1 papA3 (requalified) — acyltransferase PapA3 papA3 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c pks7 (requalified) — type I polyketide synthase pks7 pks8 (requalified) — polyketide synthase pks8 fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 fas (requalified) — fatty acid synthase fas Rv3074 (family_assigned) — DUF222 domain-containing protein Rv3074 Rv1378c (family_assigned) — hypothetical protein Rv1378c Rv2100 (family_assigned) — hypothetical protein Rv2100 Rv1765c (family_assigned) — hypothetical protein Rv1765c Rv2015c (requalified) — HNH endonuclease signature motif containing protei Rv2015c Rv1702c (requalified) — HNH endonuclease signature motif containing protei Rv1702c fadB2 (requalified) — 3-hydroxybutyryl-CoA dehydrogenase FadB2 fadB2 fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 fadE7 (requalified) — acyl-CoA dehydrogenase fadE7 fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE4 (family_assigned) — acyl-CoA dehydrogenase family protein fadE4 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD fadD30 (requalified) — long-chain-fatty-acid--AMP ligase FadD30 fadD30 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.