Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3754 · 46 genes shown · anchor tadA · open gene page → · ← back to 1 hop

Evidence: Min score 0
tyrA (requalified) — prephenate dehydrogenase TyrA tyrA hisC2 (requalified) — histidinol-phosphate transaminase hisC2 hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 cobC (requalified) — aminotransferase cobC Rv0948c (requalified) — chorismate mutase Rv0948c pheA (requalified) — prephenate dehydratase pheA Rv1885c (requalified) — chorismate mutase Rv1885c Rv3242c (family_assigned) — ComF family protein Rv3242c aroF (requalified) — chorismate synthase aroF apt (requalified) — adenine phosphoribosyltransferase apt xerC (requalified) — tyrosine recombinase XerC xerC wbbL1 (requalified) — N-acetylglucosaminyl-diphospho-decaprenol L-rhamno wbbL1 Rv3753c (family_assigned) — hypothetical protein Rv3753c hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisD (requalified) — histidinol dehydrogenase hisD hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobQ1 (requalified) — cobyric acid synthase cobQ1 aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG trpE (requalified) — anthranilate synthase component I trpE fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c hemY (requalified) — protoporphyrinogen oxidase hemY nagA (requalified) — N-acetylglucosamine-6-phosphate deacetylase nagA aroB (requalified) — 3-dehydroquinate synthase aroB aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroK (requalified) — shikimate kinase AroK aroK Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purB (requalified) — adenylosuccinate lyase purB purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH gmk (requalified) — guanylate kinase gmk deoD (requalified) — purine-nucleoside phosphorylase deoD adoK (family_assigned) — carbohydrate kinase family protein adoK Rv2646 (requalified) — tyrosine-type recombinase/integrase Rv2646 viuB (requalified) — siderophore-interacting protein viuB whiA (family_assigned) — DNA-binding protein WhiA whiA rmlD (requalified) — dTDP-4-dehydrorhamnose reductase rmlD glfT1 (requalified) — galactofuranosyl transferase GlfT glfT1 rfe (requalified) — UDP-N-acetylglucosamine--decaprenyl-phosphate N-ac rfe manB (requalified) — D-alpha-D-mannose-1-phosphate guanylyltransferase manB lcp1 (requalified) — phosphotransferase Lcp1 lcp1

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.