MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3730c · 40 genes shown · anchor ligC · open gene page → · ← back to 1 hop

Evidence: Min score 0
ligD (requalified) — non-homologous end-joining DNA ligase ligD ligC (requalified) — ATP-dependent DNA ligase ligC mku (requalified) — Ku protein mku ligB (requalified) — ATP-dependent DNA ligase ligB Rv2828A (dark) — hypothetical protein Rv2828A lhr (requalified) — ATP-dependent helicase lhr Rv3732 (dark) — DUF2330 domain-containing protein Rv3732 ligA (requalified) — NAD-dependent DNA ligase LigA ligA recA (requalified) — intein-containing recombinase RecA recA Rv0269c (requalified) — DNA polymerase domain-containing protein Rv0269c lppK (family_assigned) — hypothetical protein lppK dnaN (family_assigned) — DNA polymerase III subunit beta dnaN Rv2090 (requalified) — 5'-3' exonuclease Rv2090 ligD (requalified) — ATP-dependent DNA ligase ligD uvrD1 (requalified) — ATP-dependent DNA helicase UvrD uvrD1 polA (requalified) — DNA polymerase I polA fadE22 (requalified) — acyl-CoA dehydrogenase fadE22 Rv2828c (family_assigned) — DUF1802 family protein Rv2828c vapB22 (family_assigned) — type II toxin-antitoxin system prevent-host-death vapB22 vapC22 (family_assigned) — PIN domain-containing protein vapC22 echA16 (requalified) — enoyl-CoA hydratase echA16 Rv1156 (requalified) — HhH-GPD-type base excision DNA repair protein Rv1156 nei (requalified) — endonuclease VIII Nei2 nei Rv3295 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3295 Rv3555c (family_assigned) — DUF559 domain-containing protein Rv3555c radA (requalified) — DNA repair protein RadA radA Rv2191 (family_assigned) — hypothetical protein Rv2191 Rv3242c (family_assigned) — ComF family protein Rv3242c ptrp (family_assigned) — hypothetical protein ptrp embR (requalified) — response regulator transcription factor EmbR embR Rv2113 (family_assigned) — integral membrane protein Rv2113 Rv3254 (requalified) — oxidoreductase Rv3254 Rv1775 (family_assigned) — hypothetical protein Rv1775 vapB47 (requalified) — antitoxin VapB47 vapB47 fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu Rv3015c (requalified) — methionine synthase Rv3015c leuS (requalified) — leucine--tRNA ligase leuS ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB recX (requalified) — recombination regulator RecX recX lexA (requalified) — transcriptional repressor LexA lexA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.