MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3703c · 46 genes shown · anchor egtD · open gene page → · ← back to 1 hop

Evidence: Min score 0
etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE Rv3705c (family_assigned) — sensor domain-containing protein Rv3705c Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 atsB (requalified) — arylsulfatase AtsB atsB atsD (requalified) — arylsulfatase AtsD atsD Rv3077 (requalified) — hydrolase Rv3077 atsA (requalified) — arylsulfatase AtsA atsA Rv0296c (requalified) — sulfatase Rv0296c mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG hisD (requalified) — histidinol dehydrogenase hisD Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 Rv3707c (requalified) — hypothetical protein Rv3707c ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 spmT (requalified) — sphingomyelinase spmT Rv3705A (family_assigned) — hypothetical protein Rv3705A sodC (family_assigned) — superoxide dismutase family protein sodC pepN (requalified) — aminopeptidase PepN pepN pepB (requalified) — leucyl aminopeptidase pepB Rv3300c (family_assigned) — RluA family pseudouridine synthase Rv3300c Rv0712 (family_assigned) — formylglycine-generating enzyme family protein Rv0712 phoY1 (requalified) — phosphate signaling complex protein PhoU phoY1 lpqC (family_assigned) — PHB depolymerase family esterase lpqC Rv3493c (requalified) — mammalian cell entry protein Rv3493c glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2 vapC8 (family_assigned) — PIN domain-containing protein vapC8 vapB8 (requalified) — antitoxin VapB8 vapB8 Rv0666 (dark) — hypothetical protein Rv0666 glgC (requalified) — glucose-1-phosphate adenylyltransferase glgC vapC7 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC7 Rv3076 (family_assigned) — SRPBCC family protein Rv3076 hab (requalified) — hydrogenase hab iniA (requalified) — isoniazid inductible protein IniA iniA cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT rpsQ (requalified) — 30S ribosomal protein S17 rpsQ pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv0295c (family_assigned) — Stf0 family sulfotransferase Rv0295c Rv0303 (requalified) — protochlorophyllide reductase Rv0303 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.