Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3697c · 45 genes shown · anchor vapB48 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapC48 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC48 vapB48 (requalified) — antitoxin VapB48 vapB48 vapB43 (family_assigned) — ribbon-helix-helix domain-containing protein vapB43 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 glpK (requalified) — glycerol kinase GlpK glpK Rv3698 (family_assigned) — hypothetical protein Rv3698 vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 vapC4 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC4 vapB31 (family_assigned) — ribbon-helix-helix protein%2C CopG family vapB31 Rv3699 (requalified) — class I SAM-dependent methyltransferase Rv3699 Rv0743c (family_assigned) — DUF6036 family nucleotidyltransferase Rv0743c vapC12 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC12 Rv3749c (family_assigned) — hypothetical protein Rv3749c Rv0298 (family_assigned) — ribbon-helix-helix protein%2C CopG family Rv0298 vapC43 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC43 vapC37 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC37 mpt83 (requalified) — cell surface glycolipoprotein Mpt83 mpt83 dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr rip (requalified) — zinc metalloprotease Rip rip Rv0278c (family_assigned) — PE-PGRS family protein PE_PGRS3 Rv0278c glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2 mpa (requalified) — proteasome ATPase mpa mec (requalified) — CysO-cysteine peptidase mec glpD1 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD1 prcB (family_assigned) — proteasome subunit beta prcB prcA (family_assigned) — proteasome subunit alpha prcA Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv0857 (family_assigned) — hypothetical protein Rv0857 vapC5 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC5 vapC8 (family_assigned) — PIN domain-containing protein vapC8 vapC47 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC47 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv3479 (requalified) — transmembrane protein Rv3479 vapB4 (requalified) — type II toxin-antitoxin system antitoxin VapB4 vapB4 Rv0597c (family_assigned) — ATP-binding protein Rv0597c PE_PGRS10 (family_assigned) — PE-PGRS family protein PE_PGRS10 PE_PGRS10 vapC33 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC33 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv0745 (family_assigned) — hypothetical protein Rv0745 Rv1682 (family_assigned) — hypothetical protein Rv1682

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.