MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3661 · 36 genes shown · anchor dapD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3661 (family_assigned) — HAD-IB family hydrolase Rv3661 hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB serC (requalified) — phosphoserine transaminase serC ribH (requalified) — 6%2C7-dimethyl-8-ribityllumazine synthase ribH hisD (requalified) — histidinol dehydrogenase hisD hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 dapD (requalified) — 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxyla dapD cobC (requalified) — aminotransferase cobC serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 serA2 (requalified) — D-3-phosphoglycerate dehydrogenase SerA serA2 thrC (requalified) — threonine synthase thrC serB2 (requalified) — phosphoserine phosphatase SerB serB2 Rv3684 (requalified) — lyase Rv3684 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 ribC (requalified) — riboflavin synthase ribC metK (requalified) — S-adenosylmethionine synthetase metK mscL (requalified) — large-conductance mechanosensitive channel protein mscL ribG (requalified) — bifunctional diaminohydroxyphosphoribosylaminopyri ribG hisG (requalified) — ATP phosphoribosyltransferase hisG dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB dapC (requalified) — pyridoxal phosphate-dependent aminotransferase dapC argD (requalified) — acetylornithine transaminase argD dapE (requalified) — succinyl-diaminopimelate desuccinylase DapE dapE guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA amiA1 (requalified) — N-acyl-L-amino acid amidohydrolase AmiA amiA1 Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c tyrA (requalified) — prephenate dehydrogenase TyrA tyrA cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobQ1 (requalified) — cobyric acid synthase cobQ1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.