Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3622c · 39 genes shown · anchor PPE65 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE32 (family_assigned) — PE family protein PE32 PE32 PPE65 (family_assigned) — PPE family protein PPE65 PPE65 esxW (requalified) — type VII secretion system protein EsxW esxW esxV (requalified) — ESAT-6 like protein EsxV esxV Rv1115 (family_assigned) — hypothetical protein Rv1115 Rv2654c (requalified) — type II toxin-antitoxin system antitoxin Rv2654c rpmH (requalified) — 50S ribosomal protein L34 rpmH rplU (requalified) — 50S ribosomal protein L21 rplU Rv0373c (family_assigned) — aerobic carbon-monoxide dehydrogenase large subuni Rv0373c PE8 (family_assigned) — PE family protein PE8 PE8 ephA (requalified) — epoxide hydrolase EphA ephA esxI (requalified) — type VII secretion system ESX-5 protein EsxL esxI esxO (requalified) — type VII secretion system effector EsxO esxO esxN (requalified) — ESAT-6 like protein EsxN esxN esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP esxK (requalified) — type VII secretion system ESX-5 protein EsxJ esxK Rv1116 (dark) — hypothetical protein Rv1116 vapB32 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB32 vapC32 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC32 Rv1111c (family_assigned) — DUF6542 domain-containing protein Rv1111c Rv3094c (family_assigned) — acyl-CoA dehydrogenase family protein Rv3094c Rv0987 (family_assigned) — FtsX-like permease family protein Rv0987 Rv2656c (dark) — DUF2742 domain-containing protein Rv2656c Rv2655c (family_assigned) — DUF3631 domain-containing protein Rv2655c Rv2657c (family_assigned) — helix-turn-helix domain-containing protein Rv2657c Rv2658c (family_assigned) — hypothetical protein Rv2658c Rv2659c (requalified) — tyrosine-type recombinase/integrase Rv2659c Rv2653c (requalified) — type II toxin-antitoxin system toxin Rv2653c rpmI (requalified) — 50S ribosomal protein L35 rpmI rpsP (requalified) — 30S ribosomal protein S16 rpsP rpmA (requalified) — 50S ribosomal protein L27 rpmA rpsO (requalified) — 30S ribosomal protein S15 rpsO rpmJ (requalified) — 50S ribosomal protein L36 rpmJ rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY rpmE (requalified) — 50S ribosomal protein L31 rpmE rplR (requalified) — 50S ribosomal protein L18 rplR rplQ (requalified) — 50S ribosomal protein L17 rplQ

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.