MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3621c · 46 genes shown · anchor PE32 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE65 (family_assigned) — PPE family protein PPE65 PPE65 PE32 (family_assigned) — PE family protein PE32 PE32 Rv0373c (family_assigned) — aerobic carbon-monoxide dehydrogenase large subuni Rv0373c esxW (requalified) — type VII secretion system protein EsxW esxW esxV (requalified) — ESAT-6 like protein EsxV esxV PE8 (family_assigned) — PE family protein PE8 PE8 ephA (requalified) — epoxide hydrolase EphA ephA metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 arfC (family_assigned) — hypothetical protein arfC rplU (requalified) — 50S ribosomal protein L21 rplU PE26 (family_assigned) — PE family protein PE26 PE26 PE_PGRS5 (family_assigned) — PE-PGRS family protein PE_PGRS5 PE_PGRS5 Rv1115 (family_assigned) — hypothetical protein Rv1115 Rv2654c (requalified) — type II toxin-antitoxin system antitoxin Rv2654c rpmH (requalified) — 50S ribosomal protein L34 rpmH Rv0374c (family_assigned) — (2Fe-2S)-binding protein Rv0374c Rv0375c (family_assigned) — carbon monoxyde dehydrogenase medium subunit Rv0375c Rv0372c (family_assigned) — XdhC family protein Rv0372c Rv0370c (family_assigned) — MoxR family ATPase Rv0370c Rv0371c (family_assigned) — NTP transferase domain-containing protein Rv0371c Rv0368c (family_assigned) — VWA domain-containing protein Rv0368c esxI (requalified) — type VII secretion system ESX-5 protein EsxL esxI esxO (requalified) — type VII secretion system effector EsxO esxO esxN (requalified) — ESAT-6 like protein EsxN esxN esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP esxK (requalified) — type VII secretion system ESX-5 protein EsxJ esxK PPE15 (family_assigned) — PPE family protein PPE15 PPE15 PPE43 (family_assigned) — PPE family protein PPE43 PPE43 PPE44 (family_assigned) — PPE family protein PPE44 PPE44 Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ Rv3618 (requalified) — LLM class flavin-dependent oxidoreductase Rv3618 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC cbs (requalified) — cystathionine beta-synthase cbs metH (requalified) — methionine synthase metH cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC guaB2 (requalified) — IMP dehydrogenase guaB2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.