MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3615c · 46 genes shown · anchor espA · open gene page → · ← back to 1 hop

Evidence: Min score 0
espC (requalified) — type VII secretion system ESX-1 filament-forming t espC espA (requalified) — type VII secretion system ESX-1 target EspA espA espD (requalified) — type VII secretion system ESX-1 target EspD espD Rv3613c (family_assigned) — hypothetical protein Rv3613c Rv3612c (dark) — hypothetical protein Rv3612c espE (requalified) — type VII secretion system ESX-1 associated protein espE espH (requalified) — type VII secretion system ESX-1 associated protein espH Rv2348c (family_assigned) — hypothetical protein Rv2348c papA1 (requalified) — acyltransferase PapA1 papA1 espR (family_assigned) — type VII secretion system ESX-1 transcriptional re espR esxH (requalified) — type VII secretion system effector EsxH esxH phoR (requalified) — sensory box histidine kinase PhoR phoR TB8.4 (requalified) — hemophore-related protein TB8.4 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 espL (requalified) — type VII secretion system ESX-1 associated protein espL eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 lipQ (family_assigned) — alpha/beta hydrolase lipQ trxA (family_assigned) — thioredoxin family protein trxA esxA (requalified) — ESAT-6 protein EsxA esxA espG1 (requalified) — type VII secretion system ESX-1 adaptor EspG1 espG1 espI (family_assigned) — MinD/ParA family protein espI PPE68 (family_assigned) — PPE family protein PPE68 PPE68 PPE34 (family_assigned) — PPE family protein PPE34 PPE34 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espF (requalified) — type VII secretion system ESX-1 associated protein espF esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP PPE38 (family_assigned) — PPE family protein PPE38 PPE38 plcC (requalified) — phospholipase C plcC esxO (requalified) — type VII secretion system effector EsxO esxO plcB (requalified) — membrane-associated phospholipase B plcB plcA (requalified) — membrane-associated phospholipase A plcA pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mmpL8 (requalified) — sulfolipid-1 RND transporter MmpL8 mmpL8 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv0882 (dark) — DUF2537 domain-containing protein Rv0882 Rv3647c (family_assigned) — hypothetical protein Rv3647c Rv1109c (requalified) — lipid droplet-associated protein Rv1109c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.