Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3608c · 46 genes shown · anchor folB · open gene page → · ← back to 1 hop

Evidence: Min score 0
folP1 (requalified) — dihydropteroate synthase folP1 folB (requalified) — dihydroneopterin aldolase folB folK (requalified) — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine folK folE (requalified) — GTP cyclohydrolase I FolE folE folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH folP2 (requalified) — dihydropteroate synthase folP2 Rv0812 (requalified) — 4-amino-4-deoxychorismate lyase Rv0812 Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c Rv2366c (family_assigned) — hemolysin family protein Rv2366c Rv2365c (requalified) — cytidine deaminase Rv2365c panC (requalified) — pantoate--beta-alanine ligase panC impA (family_assigned) — inositol monophosphatase family protein impA ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 valS (requalified) — valine--tRNA ligase valS Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv3090 (family_assigned) — SPFH domain-containing protein Rv3090 rplS (requalified) — 50S ribosomal protein L19 rplS gpgS (requalified) — glucosyl-3-phosphoglycerate synthase gpgS Rv1005c (requalified) — para-aminobenzoate synthase component I Rv1005c trpG (requalified) — anthranilate synthase component II trpG ilvD (requalified) — dihydroxy-acid dehydratase ilvD Rv0811c (family_assigned) — folate-binding protein YgfZ Rv0811c Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv2367c (requalified) — endoribonuclease Rv2367c phoH1 (requalified) — phosphate starvation-inducible protein PhoH phoH1 era (requalified) — GTPase Era era Rv2369c (dark) — hypothetical protein Rv2369c Rv2370c (family_assigned) — PucR family transcriptional regulator Rv2370c mec (requalified) — CysO-cysteine peptidase mec panD (requalified) — aspartate 1-decarboxylase panD Rv3600c (requalified) — type III pantothenate kinase Rv3600c panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB Rv3603c (family_assigned) — Rossmann-like and DUF2520 domain-containing protei Rv3603c gadB (requalified) — glutamate decarboxylase gadB Rv2573 (requalified) — 2-dehydropantoate 2-reductase Rv2573 hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB suhB (requalified) — inositol-1-monophosphatase SuhB suhB

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.