Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3596c · 40 genes shown · anchor lsr2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 dnaK (requalified) — molecular chaperone DnaK dnaK Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2264c (family_assigned) — Hsp70 family protein Rv2264c grpE (requalified) — nucleotide exchange factor GrpE grpE lsr2 (requalified) — histone-like nucleoid-structuring protein Lsr2 lsr2 dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 hsp (requalified) — stress-responsive chaperone Acr2 hsp clpX (family_assigned) — ATP-dependent Clp protease ATP-binding subunit Clp clpX tig (requalified) — trigger factor tig clpB (requalified) — chaperone protein ClpB clpB Rv3716c (family_assigned) — YbaB/EbfC family nucleoid-associated protein Rv3716c Rv1332 (family_assigned) — transcriptional regulator Rv1332 Rv1333 (family_assigned) — P1 family peptidase Rv1333 mec (requalified) — CysO-cysteine peptidase mec clpC2 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC2 groES (requalified) — chaperonin GroES groES hspR (family_assigned) — heat shock transcriptional regulator HspR hspR htpG (requalified) — molecular chaperone HtpG htpG pirG (requalified) — exported repetitive protein pirG Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 groEL1 (requalified) — chaperonin GroEL groEL1 groEL2 (requalified) — chaperonin GroEL groEL2 panD (requalified) — aspartate 1-decarboxylase panD panC (requalified) — pantoate--beta-alanine ligase panC Rv3600c (requalified) — type III pantothenate kinase Rv3600c Rv3603c (family_assigned) — Rossmann-like and DUF2520 domain-containing protei Rv3603c Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv2372c (requalified) — 16S rRNA (uracil(1498)-N(3))-methyltransferase Rv2372c hrcA (requalified) — heat-inducible transcriptional repressor HrcA hrcA nirD (family_assigned) — nitrite reductase small subunit NirD nirD fxsA (family_assigned) — FxsA family protein fxsA

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.