MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3594 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3594 (requalified) — N-acetylmuramoyl-L-alanine amidase Rv3594 Rv1230c (family_assigned) — lytic transglycosylase domain-containing protein Rv1230c Rv1443c (family_assigned) — hypothetical protein Rv1443c espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 Rv1288 (requalified) — esterase Rv1288 lppF (requalified) — haloacid dehalogenase-like hydrolase lppF eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 Rv2164c (family_assigned) — hypothetical protein Rv2164c PE_PGRS30 (family_assigned) — PE-PGRS family protein PE_PGRS30 PE_PGRS30 iniB (requalified) — isoniazid-induced protein IniB iniB lpqF (requalified) — serine hydrolase lpqF Rv0613c (family_assigned) — SEC-C domain-containing protein Rv0613c mrp (family_assigned) — Mrp/NBP35 family ATP-binding protein mrp Rv1231c (family_assigned) — DUF1003 domain-containing protein Rv1231c Rv1232c (requalified) — magnesium transporter Rv1232c Rv3365c (requalified) — sensor histidine kinase Rv3365c Rv1754c (requalified) — DUF4185 domain-containing protein Rv1754c lprI (family_assigned) — MliC family protein lprI espB (requalified) — type VII secretion system ESX-1 target EspB espB PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 espI (family_assigned) — MinD/ParA family protein espI esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 Rv1287 (family_assigned) — RrF2 family transcriptional regulator Rv1287 Rv1289 (family_assigned) — hypothetical protein Rv1289 Rv0097 (family_assigned) — TauD/TfdA family dioxygenase Rv0097 Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF Rv2319c (requalified) — universal stress protein Rv2319c mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 pbpB (requalified) — D%2CD-transpeptidase PbpB pbpB ftsQ (requalified) — cell division protein FtsQ ftsQ rsmH (requalified) — 16S rRNA (cytosine(1402)-N(4))-methyltransferase R rsmH mraZ (requalified) — division/cell wall cluster transcriptional repress mraZ ptrp (family_assigned) — hypothetical protein ptrp Rv3909 (dark) — hypothetical protein Rv3909 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 Rv2209 (requalified) — MFS transporter Rv2209 Rv1004c (family_assigned) — hypothetical protein Rv1004c PPE54 (family_assigned) — PPE family protein PPE54 PPE54 iniA (requalified) — isoniazid inductible protein IniA iniA iniC (requalified) — isoniazid-induced dynamin-like GTPase IniC iniC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.