MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3534c · 44 genes shown · anchor hsaG · open gene page → · ← back to 1 hop

Evidence: Min score 0
hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE Rv3538 (requalified) — dehydrogenase Rv3538 kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD leuB (requalified) — 3-isopropylmalate dehydrogenase leuB leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvE (requalified) — branched-chain amino acid aminotransferase ilvE Rv0812 (requalified) — 4-amino-4-deoxychorismate lyase Rv0812 leuA (requalified) — 2-isopropylmalate synthase leuA fadA5 (requalified) — steroid 3-ketoacyl-CoA thiolase fadA5 aldA (requalified) — aldehyde dehydrogenase aldA hsaD (requalified) — alpha/beta fold hydrolase hsaD ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c Rv3548c (family_assigned) — SDR family oxidoreductase Rv3548c Rv0148 (family_assigned) — SDR family oxidoreductase Rv0148 Rv3502c (requalified) — 3-oxoacyl-ACP reductase Rv3502c fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 fabG4 (requalified) — 3-oxoacyl-ACP reductase fabG4 kshA (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase subunit KshA kshA sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC Rv0760c (family_assigned) — ketosteroid isomerase family protein Rv0760c kshB (family_assigned) — 3-ketosteroid-9-alpha-hydroxylase reductase subuni kshB Rv1817 (family_assigned) — FAD-binding protein Rv1817 ilvN (family_assigned) — acetolactate synthase small subunit ilvN serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC metB (requalified) — cystathionine gamma-synthase metB panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA Rv1005c (requalified) — para-aminobenzoate synthase component I Rv1005c folP1 (requalified) — dihydropteroate synthase folP1 folP2 (requalified) — dihydropteroate synthase folP2 trpG (requalified) — anthranilate synthase component II trpG Rv0811c (family_assigned) — folate-binding protein YgfZ Rv0811c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.